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William M. Seymour's avatar

Very good question! I don’t know offhand. Perhaps this is the mechanism for toxicity by some antibiotics, depending on dose.

William M. Seymour's avatar

Thank you, that transfer idea is very interesting.

William M. Seymour's avatar

It plays a role in the electron transport chain. I’m going to cover in the upcoming post, Part II.

Thanks for reading.

WS

Mark Seager's avatar

So if mitochondria are bacterial in origin what effect does antibiotics have on them?

Dmitry's avatar

Very interesting — it looks like mitochondria and mitochondrial transfer are truly at the cutting edge of research and potential therapies. Some clinical trials even seem to be already underway, which makes this field even more exciting to follow. Very interesting article: https://www.nature.com/articles/s42255-024-01200-x Recommendations for mitochondria transfer and transplantation nomenclature and characterization

Edmund Esterbauer's avatar

Does Co-Enzyme 10 help maintain mitochondrial integrity as claimed by herbal suppliers.

Martha Carlin's avatar

I’m so glad you called out that no single biomarker tells the whole story for mitochondrial function. The adenylate energy charge is such an elegant metric, and yet it’s so often relegated to textbooks.

William M. Seymour's avatar

Thanks for the feedback Martha, I appreciate it. If I Google mitochondria as a key word it seems the whole world has something to say or something to sell. I hope a clearer picture will emerge in the near future. W.S.